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Crosscutting Area(s)
Human Health and Countermeasures
 
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Bone Loss
 
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4 Risks found.
1 Accelerated Bone Loss and Fracture Risk
2 Impaired Fracture Healing
3 Injury to Joints and Intervertebral Structures
4 Renal Stone Formation
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Bone Loss Sensory-Motor Adaptation Advanced Environmental Monitoring & Control
Cardiovascular Alterations Nutrition Advanced Extravehicular Activity
Environmental Health Clinical Capabilities Advanced Food Technology
Immunology & Infection Behavioral Health & Performance and Space Human Factors (Cognitive) Advanced Life Support
Skeletal Muscle Alterations Radiation Space Human Factors Engineering
 
Bone Loss

Bones of the legs, pelvis and spine are subject to decreased stress in weightlessness, leading to the release of calcium, leaving the bone more brittle and weak. Risks include: acceleration of age-related osteoporosis; fracture and impaired fracture healing; injury to soft connective tissue and joint cartilage, and intervertebral disc rupture; and renal stone formation. It is unknown whether these changes continue unabated, nor whether they can be totally reversed. Countermeasure research and technology efforts focus on diagnostic tools to monitor and measure critical parameters, including the cellular and molecular mechanisms of bone loss. Prevention and rehabilitation involves pharmacological, exercise and nutritional regimens, artificial gravity options, and crew screening and selection criteria to identify "at risk" individuals.
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Last Updated : Feb. 9, 2005