Disciplines
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Immunology & Infection
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Systematic research utilizing both animal and human studies will determine the effect of long duration space flight on immune system changes. Risks include infections, carcinogenesis, altered hemodynamics from changes in blood components, altered wound healing, altered host-microbial interactions, and allergies and hypersensitivities. Reliable predictions of immune compromise are required, as are a better understanding of neuroendocrine stress, psychological stress and other synergistic factors on immune responses. Countermeasures include environmental monitoring systems, immune system activators, viral suppression agents, antiseptic treatments, wound healing promoters, antibiotic susceptibility testing, preflight screening criteria, inflight microbial identification capability, and hematological monitoring.
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