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    Arch Dis Child. 2003 Mar;88(3):222-3.

    Bacterial infections, immune overload, and MMR vaccine. Measles, mumps, and rubella.

    Miller E, Andrews N, Waight P, Taylor B.

    Immunisation Division, Communicable Disease Surveillance Centre, Public Health Laboratory Service, 61 Colindale Avenue, London NW9 5EQ, UK. emiller@phls.org.uk

    Abstract

    Combined measles, mumps, and rubella (MMR) vaccine did not increase the risk of hospitalisation with invasive bacterial infection in the three months after vaccination; rather there was a protective effect. These results provide no support for the concept of "immunological overload" induced by multiple antigen vaccinations, nor calls for single antigen vaccines.

    PMID: 12598383 [PubMed - indexed for MEDLINE]PMCID: PMC1719482Free PMC Article

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