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SDAP - Structural Database of Allergenic Proteins
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SDAP is a Web server
that integrates a database of allergenic proteins with various computational
tools that can assist structural biology studies related to allergens.
SDAP is an important tool in the investigation of the cross-reactivity between known allergens,
in testing the FAO/WHO allergenicity rules for new proteins, and in
predicting the IgE-binding potential of genetically modified food proteins.
Using this Internet service through a browser, it is possible to retrieve information related to an
allergen from the most common protein sequence and structure databases (SwissProt, PIR, NCBI, PDB),
to find sequence and structural neighbors for an allergen, and to search for the presence of an epitope
other the whole collection of allergens.
Read an SDAP Overview or select a SDAP function from the left column.
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The SDAP project is supported by
a contract from the U.S. Food and Drug Administration (HHSF223200710011I),
and grants from the National Institute of Health (R01 AI 064913),
and the U.S. Environmental Protection Agency under a STAR Research Assistance Agreement (No. RD 833137).
Recent SDAP developments:
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