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Epcam
Gene Detail
 Symbol
Name
ID
Epcam
epithelial cell adhesion molecule
MGI:106653
Synonyms CD326, EGP-2, Egp314, Ep-CAM, EpCAM, GA733-2, gp40, Ly74, panepithelial glycoprotein 314, Tacstd1, TROP1
Feature Type protein coding gene
Genetic Map
Chromosome 17
57.87 cM
Detailed Genetic Map ± 1 cM
 
Mapping data( 2)

Sequence Map
Chr17:88035319-88050446 bp, + strand
(From Ensembl annotation of NCBI Build 37)
Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser
Mammalian
homology
human; chimpanzee; cattle; dog, domestic; rat    (Mammalian Orthology)
Comparative Map (Mouse/Human Epcam ± 2 cM)
Protein SuperFamily: epithelial glycoprotein antigen GA733
TreeFam: TF332767
Sequences
Representative Sequences Length Strain/Species Flank
genomic ENSMUSG00000045394 Ensembl Gene Model | MGI Sequence Detail 15128 C57BL/6J ± Kb
transcript ENSMUST00000053577 Ensembl | MGI Sequence Detail 2040 Not Applicable
polypeptide ENSMUSP00000061935 Ensembl | MGI Sequence Detail 315 Not Applicable
For the selected sequences
All sequences(23) RefSeq(2) UniProt(1)
Alleles
and
phenotypes 		All alleles(8) : Gene trapped(8)
Homozygous null mice display embryonic lethality during organogenesis with decreased embryo size, impaired labyrinth layer development and decreased number of trophoblast giant cells.
Polymorphisms SNPs within 2kb(34 from dbSNP Build 128)  
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process positive regulation of cell proliferation
Component apical plasma membrane, basolateral plasma membrane...
External Resources: FuncBase
Expression Literature Summary: (18 records)
Data Summary: Assays (5)    Results (350)    Tissues (80)    Images (41)
Theiler Stages: 19,20,22,23,28
  Assay Type Assays   Results
      RNA in situ 4   344
      Immunohistochemistry 1   6
cDNA source data(394)
External Resources: Allen Brain Atlas  GENSAT  GEO  ArrayExpress 
Molecular
reagents 		All nucleic(396) Genomic(1) cDNA(394) Primer pair(1) Antibodies(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000045394 (Evidence)
Entrez Gene 17075 (Evidence)
UniGene 4259
DFCI TC1573557
DoTS DT.101124579, DT.101385250, DT.101385252, DT.87072498, DT.94131074
NIA Mouse Gene Index U018324
Consensus CDS Project CCDS29018.1
International Mouse Knockout Project Status Epcam
Protein-related
information
Resource ID Description
InterPro IPR000716 Thyroglobulin type-1
References
(Earliest) J:10429 Timblin C et al., "Application for PCR technology to subtractive cDNA cloning: identification of genes expressed specifically in murine plasmacytoma cells." Nucleic Acids Res 1990 Mar 25;18(6):1587-93
(Latest) J:169829 Pyrgaki C et al., "Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion." Dev Biol 2011 Mar 4;():
All references(29)
Other
accession IDs 		MGD-MRK-35111, MGD-MRK-35182
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/18/2011
MGI_4.41
Web browser compatibility 		The Jackson Laboratory